2012年6月10日星期日

Usage of Hexamethyldisiloxane




Product name: Hexamethyldisiloxane
CAS:107-46-0
Molecular Formula:C6H18OSi2
Formula Weight:162.38g/mol
Description of  Hexamethyldisiloxane:
Abbreviations:HMDSO, (TMS)2O
Uses:
Hexamethyldisiloxane is mainly used as source of the trimethylsilyl functional group (-Si(CH3)3) in organic synthesis. For example, in the presence of acid catalyst, it converts alcohols and carboxylic acids into the silyl ethers and silyl esters, respectively.
HMDS is used as an internal standard for calibrating chemical shift in1H NMR spectroscopy. It is more easily handled since it is less volatile than the usual standard tetramethylsilane but still displays only a singlet near 0 ppm.
HMDS has even poorer solvating power than alkanes. It is therefore sometimes employed to crystallize highly lipophilic compounds.
It is also used in liquid bandages (spray on plasters) such as cavilon spray, to protect damaged skin from irritation from other bodily fluids.
HMDSO is being studied for making low-k dielectric materials for the semi-conductor industries by PECVD (plasma-enhanced chemical vapor deposition).
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